Salicylates may be prescribed therapeutically to prevent clot formation in patients on long term bed rest with fractures or in the prevention of heart attacks. 2. Gastrointestinal Disturbances a. __________________________________________ can cause gastritis and GI bleeding. b. Contraindicated for persons with ulcer disease. c. Give with food. 3. Liver a. ____________________________ can cause liver toxicity

especially with an overdose or when alcohol is being consumed. b. NSAIDs can affect liver enzymes. Monitor blood values. 4. Renal toxicity: a. High doses of __________________________________ can cause renal failure. b. NSAIDs can cause hematuria and acute renal failure. 5. Hearing: Tinnitus (ringing in the ears) is the first sign of _____________________________________________ 6. Allergic reaction: Allergies to salicylates are quite common. Causes asthma symptoms. Patients who are allergic to salicylates may also be allergic to Naprosyn. 7. Antidote for acetaminophen overdose is acetylcysteine (Mucomyst) E. Antiheadache 1. Sumatriptan (Imitrex) 2. Actions: Constricts cerebral arteries 3. Forms _________________________________________ _________________________________________ c. _________________________________________ 4. Adverse reactions: _______________________________________ b. ______________________________________ 5. Teach patient to look for triggers for migraine headaches IV. Narcotic Analgesics A. Narcotic analgesics alter the ______________________________ B. Side effects 1. Respiratory _____________________________________ 2. Drop in ________________________________________ 3. Decreased alertness 4. Cough ________________________________________ 5. Decreased _____________________________________ 6. ________________________________________ pupils 7. ______________________________intracranial pressure 8. Addictive potential 9. Alcohol potentiates CNS depressant effects of narcotics. 10. Urinary_________________________________________ 11. ______________________________________________ Oral and parenteral dosages are not the same. Oral doses are ________________________than I.M. doses. D. Examples of Drugs 1. Morphine 2. Codeine 3. Meperidine (Demerol) 4. Methadone (Dolophine) 5. Hydromorphone HCl (Dilaudid) 6. Pentazocine HCl (Talwin) 7. Oxycodone HCl 8. Oxycodone and acetaminophen (Percocet) 9. Oxycodone and aspirin (Percodan) E. Patient Controlled Analgesia (PCA) 1. A type of intravenous pump that allows the client to administer his own narcotic analgesic on demand within preset ________________________________________ 2. Nurse must instruct patient in use of PCA pump and assess client for ________________________________________ frequently. 3. Less total analgesia