During an outbreak of severe neurological disease of unknown cause, the families of the patients suggest that the cause is adulterated cooking oil of...

Question Answered step-by-step During an outbreak of severe neurological disease of unknown cause,the families of the patients suggest that the cause is adulterated cooking oil of a particular brand. Based on considerations for causality in Table 5.1, what would you try to demonstrate first? What type of study would be suitable? At what stage would you intervene if the accumulating evidence showed that the oil might be the cause? (Bonita et al, 2006)Table 5.1. Considerations for causation (page 90, Chap 5, Bonita, 2016) -Temporal relationDoes the cause precede the effect? (essential)2.PlausibilityIs the association consistent with other knowledge? (mechanism of action; evidence from experimental animals) 3.ConsistencyHave similar results been shown in other studies?4.StrengthWhat is the strength of the association between the cause and the effect? (relative risk)5.Dose-response relationship Is increased exposure to the possible cause associated with increased effect?6.ReversibilityDoes the removal of a possible cause lead to the reduction of disease risk?7.Study designIs the evidence based on a strong study design?8.Judging the evidenceHow many lines of evidence lead to the conclusion? Health Science Science Nursing NURSING 255 Share QuestionEmailCopy link Comments (0)